Elizabeth Edgerly, Ph.D., is our chief program officer and an expert on all things research!
Just last week, we awarded a special type of grant we call an Every Day Technologies for Alzheimer’s Care grant to Dolores Gallagher-Thompson, Ph.D., professor of research in the department of Psychiatry and Behavioral Science at Stanford University for her project “Global Caregiving: iSupport for Dementia Family Caregivers.”
Caregiving for a family member with Alzheimer’s disease is a worldwide issue, and the needs of family caregivers far outpace the support from health systems, particularly in low and middle-income countries.
With this grant, Dr. Gallagher-Thompson is teaming up with the World Health Organization to develop an interactive, web-based caregiver support tool (iSupport) that is accessible via computer, tablet and mobile phone. Continue reading “New Every Day Technologies for Alzheimer’s Care Grant: Dr. Gallagher-Thompson, Stanford University” »
Many of you have seen headlines in the news that imply there is a new online test for Alzheimer’s disease. Created by researchers at Ohio State University, the test was made available online and the resulting news coverage led to so many people trying to access the test that it crashed OSU’s web site! Here’s a breakdown of the research about the Self-Administered Gerocognitive Examination (SAGE test), how it is administered and what the results actually mean.
Tests already exist that allow doctors to get a baseline measurement of cognitive function in their patients, so they can follow them and track change over time. However, they are not generally administered at home or in a community setting, but in a medical setting. Unfortunately, people with Alzheimer’s often wait years after their symptoms first appear to seek evaluation and treatment. Continue reading “Research in the news: A test for Alzheimer’s that you can take online?” »
The Journal of the American Medical Association (JAMA) recently published an article describing the results of a clinical trial of vitamin E and memantine in people with mild to moderate Alzheimer’s disease. Here is a breakdown of the story!
Alpha tocopherol, a fat-soluble vitamin (known as vitamin E) and antioxidant, has previously been studied in patients with moderately severe Alzheimer’s disease and in people with mild cognitive impairment (MCI), but has not been studied in patients with mild to moderate Alzheimer’s. In a clinical trial of people with moderately severe Alzheimer’s, vitamin E was shown to be effective in slowing clinical progression.
In this clinical trial of people with mild to moderate Alzheimer’s disease, participants receiving vitamin E had slower functional decline than those receiving placebo, with the annual rate of decline in activities of daily living reduced by 19 percent. The study authors say that this treatment effect translates into a clinically meaningful delay in progression in the vitamin E group of 6.2 months. Continue reading “Research in the news: Alzheimer’s and Vitamin E” »
We recently awarded a New Investigator Grant to Jin Hyung Lee, Ph.D., Assistant Professor, Neurology & Neurological Sciences and Bioengineering for her study “Direct Network Visualization of Alzheimer’s Drug Efficacy Using optogenetic functional MRI (ofMRI).”
Magnetic resonance imaging (MRI) is used in medical clinics to noninvasively image brain structure in living people. A version of MRI, functional MRI (fMRI), can be used to image brain activity by measuring blood flow and oxygen utilization to active brain regions. Continue reading “New Investigator Grant: Dr. Jin Hyung Lee, Stanford” »
I want to tell all of you about an event I’ll be attending next week that I am very excited about: the Bay Area premiere of a documentary film call The Genius of Marian. The film, by local filmmaker Banker White, focuses on his mother as her Alzheimer’s disease advances. If you are in or near San Francisco on November 23, I highly recommend you get tickets – plus, I’ll be moderating a conversation with Banker and film producer Anna Fitch immediately following the screening. Details on the event appear at the bottom of this post. I asked Banker to tell us a bit about the film and his family’s journey with Alzheimer’s disease. Here’s what he had to say:
The Genius of Marian is a documentary film about my extraordinary mother Pam White, and her struggle with early-onset Alzheimer’s disease. The last few years have been a roller coaster of emotions, filled with frustration, sadness, joy and celebration. I didn’t originally set out to make a documentary film about my mother’s disease. The project began as a series of informal recorded conversations with my mom in the months after her Alzheimer’s diagnosis in 2009. She had begun writing a memoir called “The Genius of Marian” about her own mother (my grandmother), Marian Williams Steele. Marian was a well-loved and well-known painter and was in many ways the matriarch of our family. In 2001, Marian died of Alzheimer’s disease at the age of 89. Continue reading “SATURDAY: The Genius of Marian in San Francisco” »